The program DS4 Windows allows use of a controller on a computer by allocating controller buttons to keys/mouse movements. Thus allowing access to a computer using a controller.

The program will run fine and all the button inputs will work, until you click on an open Minecraft tab after which the program will not respond to any of your inputs. If you then proceed to unclick the tab via a mouse or any other device that does not use DS4 Windows, the controller inputs will immediately start to work again.

This isn't a problem with DS4 Windows as it works perfectly fine with all other programs and applications, Minecraft is the exception

EDIT: DS4 Windows works with previous versions of Minecraft so it is something that has changed in recent updates