When I play Minecraft Java in a single player world and run Minecraft Plus (screen saver) because I don't interact with the pc for a while. When I'm not in the Esc menu or chat. And I press a button to stop the screen saver. Then I can't interact with the cursor in Minecraft. To solve the problem, I just have to change the display on which Minecraft is running to another one.

I've only tested it with version 1.16.4.