Since updating from Beta 1.2.13.11 to 1.2.13.12 on Windows 10, you cannot use the mouse and controller together. Example, When the xbox controller is plugged in you can look around with the mouse but if you open a chest or your inventory the game no longer recognizes the mouse. You have to use the xbox controller to move items and to even move the courser. Unplug the controller and the mouse works as expected.